Oguchi Disease Associated with Keratoconus
نویسندگان
چکیده
منابع مشابه
ERG rod a-wave in Oguchi disease
We analyzed the change in the ERG rod a-wave waveform during the course of dark adaptation in two patients with Oguchi disease. Two Japanese patients showed a homozygous arrestin 1147delA mutation. Scotopic flash ERGs were recorded after different periods of dark adaptation. ERG rod a-waves were obtained after subtraction of the cone ERG contribution. The rod a-waves were fitted with a model of...
متن کاملKeratocyte apoptosis associated with keratoconus.
Keratoconus is an ectatic corneal dystrophy associated with stromal thinning and disruption of Bowman's layer. The purpose of this study was to explore a possible association between keratocyte apoptosis and keratoconus. Keratocyte apoptosis was evaluated in corneas of patients with keratoconus, corneas of patients with stromal dystrophies, and normal donor corneas using the transferase-mediate...
متن کاملAchondroplasia Associated with Bilateral Keratoconus
We report a rare case of bilateral keratoconus in association with achondroplasia. A 26-year-old male, with a known case of achondroplasia, complained of bilateral gradual deterioration in vision for the past few years. Slit lamp biomicroscopy showed bilateral central corneal protrusion and stromal thinning at the apex consistent with keratoconus. a trial of hard contact lens fitting failed to ...
متن کاملMolecular and Histopathological Changes Associated with Keratoconus
Keratoconus (KC) is a corneal thinning disorder that leads to loss of visual acuity through ectasia, opacity, and irregular astigmatism. It is one of the leading indicators for corneal transplantation in the Western countries. KC usually starts at puberty and progresses until the third or fourth decade; however its progression differs among patients. In the keratoconic cornea, all layers except...
متن کاملNo VSX1 gene mutations associated with keratoconus.
PURPOSE To determine whether mutations of the VSX1 gene play a pathogenetic role in the development of keratoconus (KTCN). METHODS DNA extraction, PCR amplification, and direct sequencing of the VSX1 gene were performed in 100 unrelated patients with diagnoses of clinical and topographic features of KTCN. RESULTS Of the four previously identified presumed pathogenic mutations in the VSX1 ge...
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ژورنال
عنوان ژورنال: Journal of Ophthalmic and Vision Research
سال: 2021
ISSN: 2008-322X,2008-2010
DOI: 10.18502/jovr.v16i1.8262